Ewing's Sarcoma: Development of RNA Interference-Based Therapy for Advanced Disease
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چکیده
منابع مشابه
Ewing's Sarcoma: Development of RNA Interference-Based Therapy for Advanced Disease
Ewing's sarcoma tumors are associated with chromosomal translocation between the EWS gene and the ETS transcription factor gene. These unique target sequences provide opportunity for RNA interference(i)-based therapy. A summary of RNAi mechanism and therapeutically designed products including siRNA, shRNA and bi-shRNA are described. Comparison is made between each of these approaches. Systemic ...
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ژورنال
عنوان ژورنال: ISRN Oncology
سال: 2012
ISSN: 2090-567X
DOI: 10.5402/2012/247657